All 7 of the P&O Cruises fleet sail out of Southampton - Arcadia, Aurora, Azura, Britannia, Ventura and their newest ships Arvia and Iona so you will be spoiled for choice.

Our most popular P&O Cruises sailing from Southampton are: 2 weeks Mediterranean, 2 weeks Canary Islands, 1 or 2 week Northern Europe/Fjords & 2 weeks in the Caribbean. In addition we have a wide selection of other P&O cruises from Southampton ranging from South America, Eastern USA and Canada as well as the ever popular World Cruises for those looking for an adventure.

In the search results below we show the next available P&O cruises sailing from Southampton. You can filter these results by price to show the cheapest cruises at the top. Or your favourite destination, ship or holiday duration on the left. Or search the results for the date you would like to take you P&O cruise holiday from Southampton.

All of our P&O Cruises Southampton sailings have all inclusive full board dining and include all gratuities. If you would like to cover your bar tab before you embark at Southampton then you may like to consider adding on a drink package to your booking.

To find out more about which fare is best for you - Select Fare, Early Saver or Saver fares, see our guide to P&O Cruises fares.

If you need some more advice our friendly Cruise Agents are looking forward to speaking to you on 01246 819 819 or you can book your cruise online today.